Hot News

More Languages for Flyer!

posted Jul 24, 2019, 4:39 AM by Rachel Aronoff   [ updated Sep 2, 2019, 1:34 AM ]


 So excited to have had help for more super languages for the flyer - to be posted soon!!

 The flyer has a very simple message, and we hope it will help spread the word even further, with Malay, Indonesian, Marathi and more!!!  Big Thanks to Kelly from Singapore!  (and now there is already a new flag on the site, too!!)

 There's nothing like interest to help inspire more updates to this old site!
(use the contact link if *you* want to join in!)
&
Take care!

Open Science in Columbia

posted Jun 21, 2019, 9:14 PM by Rachel Aronoff   [ updated Jun 21, 2019, 9:21 PM ]

 So excited to be in Colombia and talking about genomic integrity and open science!

 Mercury is a big topic in the country, and more may be learned soon!!

 Thanks to our hosts and new friends!  Hoping to have the opportunity to explore further together!


Special Keynote Lecture (and P1 again!)

posted Jun 6, 2019, 5:34 AM by Rachel Aronoff   [ updated Jun 21, 2019, 9:25 PM ]

There are two special news items today!
 Next Thursday, 13June, there will be a keynote lecture at a UNIL symposium, entitled Sugar and cancer: not a sweet story! by Lewis C. Cantley from Cornell.  Sponsored by the Grace family, I am really looking forward to this!   Here is the program for the full symposium, with lots of interest in terms of dynamics of genomic integrity!
Additionally, some even bigger news: the lab of Hackuarium can again do P1 (biosafety level 1) experimentation, after an inspection today.  Maybe I am really going to learn more about how synthetic biology isn't just another word for molecular biology?? :)

Another Micronucleus Workshop!

posted May 9, 2019, 5:53 AM by Rachel Aronoff   [ updated May 9, 2019, 5:55 AM ]

 At the new Hackuarium labs in Ecublens (18may 14-17h), there will be another micronucleus workshop!
Come explore your *own* genomic integrity, checking out your inner cheek cells!
Here is more information in the announcement of the event in facebook!
Hope to see you there!!

Take care!

Meeting of the General Assembly 2019

posted Mar 5, 2019, 10:57 PM by Rachel Aronoff   [ updated Jun 6, 2019, 5:26 AM ]

Here it is, almost time for our 6th AGiR! General Assembly Meeting!
Can you join us in Ecublens, in the new cooperative space for Hackuarium to help?
Come to the Route de Crochy 20 at 6:30 pm on the 2nd of May (the April meeting had to be postponed!)!
If you can't come in person, use the contact form, and we can arrange your virtual presence!

Help make genomic integrity understood by the public!

See the provisional agenda below.

Presentation at Utopiana

posted Feb 27, 2019, 12:41 AM by Rachel Aronoff   [ updated Feb 27, 2019, 12:43 AM ]

What a great evening at Utopiana in Geneva yesterday, talking about citizen science and the plans for the cheek cell chips!
Thanks to Anna for the invitation and to the participants for their questions and comments!
(Hoping someone will be inspired enough to submit something for the Art Call - which is still open for all, btw! :)


Workshops in Bilbao!

posted Jan 16, 2019, 12:46 PM by Rachel Aronoff   [ updated Jan 17, 2019, 6:17 AM ]

Very excited for the opportunity to do workshops in Bilbao this weekend!  
Here is the info: https://bbkopenscience.com/


2019 Ahead!

posted Dec 26, 2018, 9:40 AM by Rachel Aronoff   [ updated Dec 26, 2018, 9:40 AM ]

Have a great end to 2018!!
Here's hoping that 2019 will be the year during which many more realise the easy things they can do to protect themselves and their loved ones!!
Take care! 

The Seventh Women in Science Switzerland Luncheon

posted Nov 8, 2018, 10:34 AM by Rachel Aronoff   [ updated Nov 13, 2018, 3:07 AM ]

What a nice afternoon in Montreux with the attendees of the 7th annual Women in Science Switzerland Luncheon, hosted by Lola Grace and highlighted by the talk of Claudia Bagna on 'Intellectual and Social Disabilities: from Molecules to Behavior.'  Her talk centered on Fragile X syndrome and autism, with some interesting points also about Alzheimer's disease, brain development and enriched environments.  I always thought of Fragile X syndrome as being less central to autism, but it turns out to be involved in about 60% of cases and the other 30% are due to an interacting protein, together regulating gene expression at synapses.  Again, from a certain perspective, one could say it is all about dynamics of genomic integrity!  The main Fragile X protein (FMR1) leads to disease when it is not expressed  (as for the BRCA genes, which in contrast are important for correct DNA repair), and the molecular mechanisms for the gene being 'turned off' (trinucleotide repeats) are well known in other diseases also (but not always affecting whether a gene is expressed or not). Again this is genomic integrity being affected, in this case at the DNA level.  

Most importantly, the neuronal connections between cells (especially dendritic spines at synapses, where localised translation can occur) are disrupted in the absence of FMR1, because the regulation of its target genes is disrupted, leading to incorrect responses to cell activation and faulty synapses.  Such 'synaptopathies' can lead to many diseases affecting brain development, cognitive function and neurodegeneration. 

The extra points in the talk about patient families and how women in science are being helped by research to help understand interview biases were also very appreciated.  

If you were there, and wonder about the AGiR! chocolate in your goodie bag, and, especially, would like to get more, maybe even to give to your friends during the upcoming holiday season, please write biolab@hackuarium.ch before 30 November, or phone directly to the master chocolate maker (from Gruyère)!  His dark chocolates, we hope, are full of flavanols that may protect genomic integrity.  The idea to do a real test of whether eating such chocolate protects genomic integrity isn't new, but maybe the current micronuclei protocols at Hackuarium (even though currently 'without walls') would allow a real test of this sometime soon.  I know that is some 'citizen science' that could get a lot of volunteers!  
Let me know if you would like to join in... :)  

Genomic integrity and Open Science in China

posted Oct 11, 2018, 4:51 PM by Rachel Aronoff   [ updated Oct 12, 2018, 9:39 PM ]

It is very exciting to be participating in GOSH2018 this year, especially looking into open-source epifluorescence possibilities during a workshop yesterday! Perhaps the group from Bath, UK has a real possibility with an updated version of their OpenFlexure scope to move the comet cell data acquisition forward! (fingers crossed!) 

Meeting members of the public was especially interesting yesterday, at xfactory! (thanks, Violet, for allowing the great party, too!).  After such discussions, I really need to make good on my pledge to update this site, to another platform, it is clear; and I am putting the new flyer translation into the Hackuarium wiki, to make sure more people can see this and share its ideas (and I include the even smaller file here, as a preview, for those who can access it here).
(thanks again to Yanwu, Vivi, and others for their help and discussions !! Maybe one day in the not too distant future there will even be a Chinese side to this AGiR! site, as the issues are so crucial to all of us.)

It will also a great honour to be able to present the Hackuarium genomic integrity projects at the Shenzhen Maker Week-GOSH conference (Oct.14) to end the trip!
Hoping the #GOSH2018 Prezi goes smoothly! :)

 万岁开放的科学! 
(Long live open science!)

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